Marijuana use is associated with an increased risk of prescription opioid misuse and use disorders. TRUE!

New research suggests that marijuana users may be more likely than nonusers to misuse prescription opioids and develop prescription opioid use disorder. The study was conducted by researchers at the National Institute on Drug Abuse (NIDA), part of the National Institutes of Health, and Columbia University.

The investigators analyzed data from the National Epidemiologic Survey on Alcohol and Related Conditions, which interviewed more than 43,000 American adults in 2001-2002, and followed up with more than 34,000 of them in 2004-2005. The analysis indicated that respondents who reported past-year marijuana use in their initial interview had 2.2 times higher odds than nonusers of meeting DSM-IV diagnostic criteria for prescription opioid use disorder by the follow-up. They also had 2.6 times greater odds of initiating prescription opioid misuse, defined as using a drug without a prescription, in higher doses, for longer periods, or for other reasons than prescribed.

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